Enamel & Co

Dentist-Owned Oral Care

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  • Dentist-Owned · Fluoride-Free · EnamelSync™ Peptide Technology

The Toothpaste Your Dentist Uses at Home.

After 20+ years of recommending oral care products to our patients, we couldn’t find a fluoride-free toothpaste that met our own clinical standards. So we created one.
  • Dentist Owned
  • Fluoride Free
  • EnamelSync™ Peptide Technology
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Explore the Science
  • Dentist-Owned & Formulated
  • Nano-Hydroxyapatite Formula
  • EnamelSync™ Peptide Technology
  • Fluoride-Free & SLS-Free
  • Exclusively at Participating Dental Offices
Years of Practice
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Our Story

We Couldn't Find It. So We Built It.

Across our 10 owned locations throughout Arizona, we’ve served over 35,000 patients. For more than two decades, we’ve recommended oral care products — and for just as long, we’ve been frustrated by what’s available.

Every fluoride-free toothpaste we tried either lacked clinical efficacy, used questionable ingredients, or simply didn’t perform. Our patients deserved better. We deserved better.

So we formulated Enamel & Co. — the toothpaste we now use at home, and the one we recommend without hesitation to every patient who walks through our doors.

Patients Served
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Owned Locations
0
Years of Practice
0 +

The Science

Built on 20 Years of
Clinical Knowledge

  • Featuring EnamelSync™ Peptide Technology — Proprietary Formula

01

Nano-Hydroxyapatite

The same mineral that makes up 97% of tooth enamel. Our nano-sized particles penetrate micro-fissures to remineralize from within — the same mechanism your body uses naturally.

02

EnamelSync™ Peptide Technology

Powered by Palmitoyl Tripeptide-1 – a clinically studied signal peptide that stimulates collagen synthesis in gum tissue.

It reduces gum inflammation, supports soft tissue healing, and helps combat gum recession by restoring firmness to the gingival tissue.

While nano-hydroxyapatite rebuilds the tooth, EnamelSync™ rebuilds the foundation around it.

03

Fluoride-Free Formula

We chose nano-hydroxyapatite over fluoride because the science is compelling and the safety profile is unmatched. No neurotoxicity concerns. Safe for the whole family.

04

SLS & Paraben Free

No sodium lauryl sulfate, no parabens, no artificial dyes. Every ingredient in Enamel & Co. was selected by dentists who would use it on their own families.

05

Airless Pump Technology

Our 2oz airless pump preserves formula integrity by eliminating air and bacteria exposure. Every pump delivers a precise, contamination-free dose — every time.

The Product

Precision Oral Care,
Crafted for Your Dentist's Office

Enamel & Co. Toothpaste

2 OZ Airless Pump · Nano-Hydroxyapatite Formula · EnamelSync™

  • Powered by EnamelSync™ Peptide Technology

$23.99

$29.99

  • Just $0.40/day — less than a cup of coffee
Add to cart
  • EnamelSync™ — Palmitoyl Tripeptide-1 for gum collagen & healing
  • Nano-Hydroxyapatite remineralizes enamel from within
  • Fluoride-free, SLS-free, paraben-free
  • Airless pump preserves formula purity
  • Available exclusively at participating dental offices
Find a Participating Office
Learn the Science

$29.99

per unit

  • Just $0.50/day — to protect your enamel
Add to cart
  • EnamelSync™ — Palmitoyl Tripeptide-1 for gum collagen & healing
  • Nano-Hydroxyapatite remineralizes enamel from within
  • Fluoride-free, SLS-free, paraben-free
  • Airless pump preserves formula purity
  • Available exclusively at participating dental offices
Find a Participating Office
Learn the Science

Why Enamel & Co.

Not All Toothpastes
Are Created Equal

FEATURE ENAMEL & CO. TOM'S OF MAINE REGULAR BRAND
EnamelSync™ Peptide Technology ✓ ✕ ✕
Nano-Hydroxyapatite ✓ ✕ ✕
Fluoride-Free ✓ ✕ ✕
SLS-Free ✓ ✓ ✕
Dentist-Owned & Formulated ✓ ✕ ✕
Airless Pump (Contamination-Free) ✓ ✕ ✕
Safe for Children ✓ ✓ ✕
Exclusively at Dental Offices ✓ ✕ ✕

Available Near You

Find Enamel & Co.
At Your Dentist's Office

Enamel & Co. is currently available at all 10 of our owned dental offices across Arizona. Each location features a premium counter display — ask your hygienist or front desk team for details.

This is intentional. We believe the best oral care products belong in the hands of dental professionals — who can recommend them in the context of your specific oral health needs.

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Available Near You

What Our Patients
Are Saying

"

I’ve been a patient for 12 years. When my dentist told me they made their own toothpaste, I didn’t hesitate. It’s the best thing I’ve ever used my hygienist noticed a difference at my next cleaning.

Sarah M.

Patient, 12 years

"

I was a bit skeptical when my dentist recommended their in-house toothpaste, but after using it for three months, I’m totally sold. My teeth feel smooth all day, and my dentist said my enamel health has noticeably improved during my last checkup.

David K.

Patient, 10 years

"

I’ve struggled with tooth sensitivity for years, so I was hesitant to switch from my regular brand. My dentist suggested trying their custom toothpaste, and it has been a complete game changer zero sensitivity now, and my hygienist praised how clean my teeth looked!

Emily R.

Patient, 2 years

Questions

Frequently Asked
Questions

What is EnamelSync™ Peptide Technology?
EnamelSync™ is our proprietary peptide complex powered by Palmitoyl Tripeptide-1 — a clinically studied signal peptide well-established in regenerative skincare and now applied to oral care. It works by signaling your cells to synthesize collagen in the gum tissue, which strengthens and plumps the gingival tissue to combat recession. It also reduces gum inflammation (providing relief from gingivitis symptoms), accelerates soft tissue healing from oral wear and tear, and supports the structural integrity of the tissues surrounding the mouth. While nano-hydroxyapatite rebuilds the tooth itself, EnamelSync™ rebuilds the foundation around it — a complete approach no other toothpaste offers.
Clinical research, including studies published in the Journal of Dentistry, shows nano-hydroxyapatite is equally effective at remineralizing enamel and reducing sensitivity. It works by directly replenishing the mineral content of your enamel — the same mechanism your body uses naturally. When combined with EnamelSync™ Peptide Technology, the remineralizing effect is further enhanced.
Yes. Unlike fluoride, nano-hydroxyapatite is non-toxic even if swallowed, making it ideal for children and families. It’s the same mineral that makes up their teeth — there’s nothing foreign about it.
Each 2oz airless pump contains approximately 60 days of toothpaste when used twice daily — about $0.50 per day at the single-unit price, or $0.40 per day with Subscribe & Save.
Enamel & Co. is available exclusively at our 10 owned dental offices across Arizona — by design. We believe the best oral care products belong in the hands of dental professionals who can recommend them in the context of your specific oral health. Ask your hygienist or front desk team at your next visit.
We stand behind every product with a 30-day satisfaction guarantee. If you’re not completely satisfied, contact us and we’ll make it right — no questions asked.